Citation: | Ying Li, Wen Yang, Xi-qiang Zheng, Chi Yao, Yi Wu. 2021: Combining passive sampling with toxicity testing to evaluate potential ecotoxicological effects of pharmaceuticals in wastewater-impacted rivers. Water Science and Engineering, 14(3): 201-209. doi: 10.1016/j.wse.2021.08.009 |
Ahrens, L., Daneshvar, A., Lau, A.E., Kreuger, J., 2015. Characterization of five passive sampling devices for monitoring of pesticides in water. J. Chromatogr. A 1405, 1-11. https://doi.org/10.1016/j.chroma.2015.05.044.
|
Aisha, A.A., Hneine, W., Mokh, S., Devier, M.H., Budzinski, H., Jaber, F., 2017. Monitoring of 45 pesticides in Lebanese surface water using polar organic chemical integrative sampler (POCIS). Ocean Sci. J. 52(3), 455-466. https://doi.org/10.1007/s12601-017-0041-4.
|
Al-Qaim, F.F., Abdullah, M.P., Othman, M.R., Latip, J., Zakaria, Z., 2014. Multi-residue analytical methodology-based liquid chromatographytime-of-flight-mass spectrometry for the analysis of pharmaceutical residues in surface water and effluents from sewage treatment plants and hospitals. J. Chromatogr. A 1345, 139-153. https://doi.org/10.1016/j.chroma.2014.04.025.
|
Alvarez, D.A., Petty, J.D., Huckins, J.N., Jones-Lepp, T.L., Getting, D.T., Goddard, J.P., Manahan, S.E., 2004. Development of a passive, in situ, integrative sampler for hydrophilic organic contaminants in aquatic environments. Environ. Toxicol. Chem. 23(7), 1640-1648. https://doi.org/10.1897/03-603.
|
Alygizakis, N.A., Gago-Ferrero, P., Borova, V.L., Pavlidou, A., Hatzianestis, I., Thomaidis, N.S., 2016. Occurrence and spatial distribution of 158 pharmaceuticals, drugs of abuse and related metabolites in offshore seawater. Sci. Total Environ. 541, 1097-1105. https://doi.org/10.1016/j.scitotenv.2015.09.145.
|
Aymerich, I., Acuna, V., Barcelo, D., Garcia, M.J.J., Petrovic, M., Poch, M., Rodriguez-Mozaz, S., Sabater, S., Schiller, D.V., Corominas, L.I., 2016. Attenuation of pharmaceuticals and their transformation products in a wastewater treatment plant and its receiving river ecosystem. Water Res. 100, 126-136. https://doi.org/10.1016/j.watres.2016.04.022.
|
Bialk-Bielińska, A., Stolte, S., Aming, J., Uebers, U., Boschen, A., Stepnowski, P., Matzke, M., 2011. Ecotoxicity evaluation of selected sulfonamides. Chemosphere 85(6), 928-933. https://doi.org/10.1016/j.chemosphere.2011.06.058.
|
Dai, G.H., Wang, B., Fu, C.C., Dong, R., Huang, J., Deng, S.B., Wang, Y.J., Yu, G., 2016. Pharmaceuticals and personal care products (PPCPs) in urban and suburban rivers of Beijing, China: Occurrence, source apportionment and potential ecological risk. Environ. Sci.: Process. Impact 18(4), 445-455. https://doi.org/10.1039/c6em00018e.
|
Ding, H.J., Wu, Y.X., Zhang, W.H., Zhong, J.Y., Lou, Q., 2017. Occurrence, distribution, and risk assessment of antibiotics in the surface water of Poyang Lake, the largest freshwater lake in China. Chemosphere 184, 137-147. https://doi.org/10.1016/j.chemosphere.2017.05.148.
|
Fedorova, G., Randak, T., Golovko, O., Kodes, V., Grabicova, K., Grabic, R., 2014. A passive sampling method for detecting analgesics, psycholeptics, antidepressants and illicit drugs in aquatic environments in the Czech Republic. Sci. Total Environ. 487, 681-687. https://doi.org/10.1016/j.scitotenv.2013.12.091.
|
Feitosa-Felizzola, J., Chiron, S., 2009. Occurrence and distribution of selected antibiotics in a small Mediterranean stream (Arc River, Southern France). J. Hydrol. 364(1-2), 50-57. https://doi.org/10.1016/j.jhydrol.2008.10.006.
|
Fernandez, C., Gonzalez-Doncel, M., Pro, J., Carbonell, G., Tarazona, J.V., 2010. Occurrence of pharmaceutically active compounds in surface waters of the Henares-Jarama-Tajo river system (Madrid, Spain) and a potential risk characterization. Sci. Total Environ. 408(3), 543-551. https://doi.org/10.1016/j.scitotenv.2009.10.009.
|
Fonseca, E., Hernandez, F., Ibanez, M., Rico, A., Pitarch, E., Bijlsma, L., 2020. Occurrence and ecological risks of pharmaceuticals in a Mediterranean river in Eastern Spain. Environ. Int. 144, 106004. https://doi.org/10.1016/j.envint.2020.106004.
|
He, Z.Q., Ohno, T., Wu, F.C., Olk, D.C., Honeycutt, C.W., Olanya, M., 2008. Capillary electrophoresis and fluorescence excitation-emission matrix spectroscopy for characterization of humic substances. Soil Sci. Soc. Am. J. 72(5), 1248-1255. https://doi.org/10.2136/sssaj2007.0305.
|
Homem, V., Santos, L., 2011. Degradation and removal methods of antibiotics from aqueous matrices-A review. J. Environ. Manag. 92(10), 2304-2347. https://doi.org/10.1016/j.jenvman.2011.05.023.
|
Hu, Y., Yan, X., Shen, Y., Di, M.X., Wang, J., 2018. Antibiotics in surface water and sediments from Hanjiang River, Central China: Occurrence, behavior and risk assessment. Ecotoxicol. Environ. Saf. 157, 150-158. https://doi.org/10.1016/j.ecoenv.2018.03.083.
|
Huang, H., Wu, J., Ye, J., Deng, J., Liang, Y.M., Liu, W., 2018. Occurrence, removal, and environmental risks of pharmaceuticals in wastewater treatment plants in south China. Front. Environ. Sci. Eng. 12(6), 7. https://doi.org/10.1007/s11783-018-1053-8.
|
Huckins, J.N., Petty, J.D., Orazio, C.E., Lebo, J.A., Clark, R.C., Gibson, V.L., Gala, W.R., Echols, K.R., 1999. Determination of uptake kinetics (sampling rates) by lipid-containing semipermeable membrane devices(SPMDs) for polycyclic aromatic hydrocarbons (PAHs) in water. Environ. Sci. Technol. 33(21), 3918-3923. https://doi.org/10.1021/es990440u.
|
Im, J.K., Kim, S.H., Noh, H.R., Yu, S.J., 2020. Temporal-spatial variation and environmental risk assessment of pharmaceuticals in tributaries of the Han River watershed, South Korea. Sci. Total Environ. 741, 140486. https://doi.org/10.1016/j.scitotenv.2020.140486.
|
Jarque, S., Pina, B., 2014. Deiodinases and thyroid metabolism disruption in teleost fish. Environ. Res. 135, 361-375. https://doi.org/10.1016/j.envres.2014.09.022.
|
Jiang, X.S., Zhu, Y.Q., Liu, L.Q., Fan, X.Q., Bao, Y.X., Deng, S.S., Cui, Y.X., Cagnetta, G., Huang, J., Yu, G., 2020. Occurrence and variations of pharmaceuticals and personal-care products in rural water bodies: A case study of the Taige canal (2018-2019). Sci. Total Environ. 762, 143138. https://doi.org/10.1016/j.scitotenv.2020.143138.
|
Kosma, C.I., Lambropoulou, D.A., Albanis, T.A., 2014. Investigation of PPCPs in wastewater treatment plants in Greece: Occurrence, removal and environmental risk assessment. Sci. Total Environ. 466, 421-438. https://doi.org/10.1016/j.scitotenv.2013.07.044.
|
Lapworth, D.J., Baran, N., Stuart, M.E., Ward, R., 2012. Emerging organic contaminants in groundwater: A review of sources, fate and occurrence. Environ. Pollut. 163, 287-303. https://doi.org/10.1016/j.envpol.2011.12.034.
|
Letzel, M., Metzner, G., Letzel, T., 2009. Exposure assessment of the pharmaceutical diclofenac based on long-term measurements of the aquatic input. Environ. Int. 35(2), 363-368. https://doi.org/10.1016/j.envint.2008.09.002.
|
Li, W.H., Shi, Y.L., Gao, L.H., Liu, J.M., Cai, Y.Q., 2012. Occurrence of antibiotics in water, sediments, aquatic plants, and animals from Baiyangdian Lake in North China. Chemosphere 89(11), 1307-1315. https://doi.org/10.1016/j.chemosphere.2012.05.079.
|
Li, Y., Yang, C.M., Bao, Y.J., Ma, X.R., Lu, G.H., 2016a. Aquatic passive sampling of perfluorinated chemicals with polar organic chemical integrative sampler and environmental factors affecting sampling rate. Environ. Sci. Pollut. Res. 23(16), 16096-16103. https://doi.org/10.1007/s11356-016-6791-1.
|
Li, Z., Sobek, A., Radke, M., 2016b. Fate of pharmaceuticals and their transformation products in four small European rivers receiving treated wastewater. Environ. Sci. Technol. 50(11), 5614-5621. https://doi.org/10.1021/acs.est.5b06327.
|
Liang, X.M., Wang, F., Li, K.B., Nie, X.P., Fang, H.S., 2020. Effects of norfloxacin nicotinate on the early life stage of zebrafish (Danio rerio):Developmental toxicity, oxidative stress and immunotoxicity. Fish Shellfish Immunol. 96, 262-269. https://doi.org/10.1016/j.fsi.2019.12.008.
|
Lin, T., Chen, Y.Q., Chen, W., 2014. Toxic effect of sulfadiazine on the growth of zebrafish embryos in the water body. J. Saf. Environ. 14(3), 324-327. https://doi.org/10.13637/j.issn.1009-6094.2014.03.072.
|
Liu, J.Y., Wei, T.Z., Wu, X., Zhong, H.B., Qiu, W.H., Zheng, Y., 2020. Early exposure to environmental levels of sulfamethoxazole triggers immune and inflammatory response of healthy zebrafish larvae. Sci. Total Environ. 703, 134724. https://doi.org/10.1016/j.scitotenv.2019.134724.
|
Liu, X.H., Lu, S.Y., Guo, M., Xi, B.D., Wang, W.L., 2018. Antibiotics in the aquatic environments: A review of lakes, China. Sci. Total Environ. 627, 1195-1208. https://doi.org/10.1016/j.scitotenv.2018.01.271.
|
Ma, B., Lu, G., Liu, F., Nie, Y., Zhang, Z., 2016. Organic UV filters in the surface water of Nanjing, China: Occurrence, distribution and ecological risk assessment. Bull. Environ. Contam. Toxicol. 96, 530-535. https://doi.org/10.1007/s00128-015-1725-z.
|
Martin, J., Camacho-Munoz, D., Santos, J.L., Aparicio, I., Alonso, E., 2012. Occurrence of pharmaceutical compounds in wastewater and sludge from wastewater treatment plants: Removal and ecotoxicological impact of wastewater discharges and sludge disposal. J. Hazard Mater. 239, 40-47. https://doi.org/10.1016/j.jhazmat.2012.04.068.
|
Maskaoui, K., Hibberd, A., Zhou, J.L., 2007. Assessment of the interaction between aquatic aolloids and pharmaceuticals facilitated by cross-flow ultrafiltration. Environ. Sci. Technol. 41(23), 8038-8043. https://doi.org/10.1021/es071507d.
|
Mazzella, N., Debenest, T., Delmas, F., 2008. Comparison between the polar organic chemical integrative sampler and the solid-phase extraction for estimating herbicide time-weighted average concentrations during a microcosm experiment. Chemosphere 73(4), 545-550. https://doi.org/10.1016/j.chemosphere.2008.06.009.
|
Morin, N., Miège, C., Coquery, M., Randon, J., 2012. Chemical calibration, performance, validation and applications of the polar organic chemical integrative sampler (POCIS) in aquatic environments. TrAC Trends Anal. Chem. (Reference Ed.) 36, 144-175. https://doi.org/10.1016/j.trac.2012.01.007.
|
Nantaba, F., Wasswa, J., Kylin, H., Palm, W.U., Bouwman, H., Kummerer, K., 2019. Occurrence, distribution, and ecotoxicological risk assessment of selected pharmaceutical compounds in water from Lake Victoria, Uganda. Chemosphere 239, 124642. https://doi.org/10.1016/j.chemosphere.2019.124642.
|
Oberoi, A.S., Jia, Y.Y., Zhang, H.Q., Khanal, S.K., Lu, H., 2019. Insights into fate and removal of antibiotics in engineered biological treatment systems:A critical review. Environ. Sci. Technol. 53(13), 7234-7264. https://doi.org/10.1021/acs.est.9b01131.
|
Ortiz de Garcia, S.A., Pinto, G.P., García-Encina, P.A., Irusta-Mata, R., 2014. Ecotoxicity and environmental risk assessment of pharmaceuticals and personal care products in aquatic environments and wastewater treatment plants. Ecotoxicology 23(8), 1517-1533. https://doi.org/10.1007/s10646-014-1293-8.
|
Pal, A., Gin, K.Y.H., Lin, A.Y.C., Reinhard, M., 2010. Impacts of emerging organic contaminants on freshwater resources: Review of recent occurrences, sources, fate and effects. Sci. Total Environ. 408(24), 6062-6069. https://doi.org/10.1016/j.scitotenv.2010.09.026.
|
Shi, X., Zhou, J.L., Zhao, H., Hou, L., Yang, Y., 2014. Application of passive sampling in assessing the occurrence and risk of antibiotics and endocrine disrupting chemicals in the Yangtze Estuary, China. Chemosphere 111, 344-351. https://doi.org/10.1016/j.chemosphere.2014.03.139.
|
Siegenthaler, P.F., Bain, P., Riva, F., Fent, K., 2016. Effects of antiandrogenic progestins, chlormadinone and cyproterone acetate, and the estrogen 17α-ethinylestradiol (EE2), and their mixtures: Transactivation with human and rainbowfish hormone receptors and transcriptional effects in zebrafish(Danio rerio) eleutero-embryos. Aquat. Toxicol. 182, 142-162. https://doi.org/10.1016/j.aquatox.2016.11.001.
|
Sui, Q., Huang, J., Deng, S.B., Chen, W.W., Yu, G., 2011. Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in different biological wastewatertreatment processes. Environ. Sci. Technol. 45(8), 3341-3348. https://doi.org/10.1021/es200248d.
|
Tang, J., Shi, T.Z., Wu, X.W., Cao, H.Q., Li, X.D., Hua, R.M., Tang, F., Yue, Y.D., 2015. The occurrence and distribution of antibiotics in Lake Chaohu, China: Seasonal variation, potential source and risk assessment. Chemosphere 122, 154-161. https://doi.org/10.1016/j.chemosphere.2014.11.032.
|
Ternes, T., Bonerz, M., Schmidt, T., 2001. Determination of neutral pharmaceuticals in wastewater and rivers by liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. A 938(1-2), 175-185. https://doi.org/10.1016/S0021-9673(01)01205-5.
|
Thiebault, T., Boussafir, M., Le Milbeau, C., 2017. Occurrence and removal efficiency of pharmaceuticals in an urban wastewater treatment plant:Mass balance, fate and consumption assessment. J. Environ. Chem. Eng. 5(3), 2894-2902. https://doi.org/10.1016/j.jece.2017.05.039.
|
Togola, A., Budzinski, H., 2007. Analytical development for analysis of pharmaceuticals in water samples by SPE and GCeMS. Anal. Bioanal. Chem. 388(3), 627-635. https://doi.org/10.1007/s00216-007-1251-x.
|
Vergauwen, L., Cavallin, J.E., Ankley, G.T., Bars, C., Gabriels, I.J., Michiels, E.D.G., Fitzpatrick, K.R., Periz-Stanacev, J., Randolph, E.C., Robinson, S.L., 2018. Gene transcription ontogeny of hypothalamicpituitary-thyroid axis development in early-life stage fathead minnow and zebrafish. Gen. Comp. Endocrinol. 266, 87-100. https://doi.org/10.1016/j.ygcen.2018.05.001.
|
Wang, C.Y., Liang, S.K., Zhang, Y., 2018. The ecological competition and grazing reverse the effects of sulfamethoxazole on plankton: A case study on characterizing community-level effect. Environ. Sci. Pollut. Res. 25(18), 17283-17288. https://doi.org/10.1007/s11356-018-1901-x.
|
Wang,L.,Ying,G.G.,Zhao,J.L.,Yang,X.B., Chen,F.,Tao,R.,Liu,S.,Zhou,L.J., 2010.Occurrence andrisk assessmentofacidicpharmaceuticalsintheYellow River, Hai River and Liao River of north China. Sci. Total Environ. 408(16), 3139-3147. https://doi.org/10.1016/j.scitotenv.2010.04.047.
|
Wang, N., Noemie, N., Hien, N.N., Huynh, T.T., Silvestre, F., Phuong, N.T., Danyi, S., Widart, J., Douny, C., Scippo, M.L., et al., 2009. Adverse effects of enrofloxacin when associated with environmental stress in tra catfish(Pangasianodon hypophthalmus). Chemosphere 77(11), 1577-1584. https://doi.org/10.1016/j.chemosphere.2009.09.038.
|
Wang, Y.H., Liu, J.Z., Du, K., Wu, C., Wu, Y., 2017. Removal of pharmaceuticals and personal care products from wastewater using algae-based technologies: A review. Rev. Environ. Sci. Biotechnol. 16(4), 717-735. https://doi.org/10.1007/s11157-017-9446-x.
|
Xie, Z., Lu, G., Liu, J., Yan, Z., Ma, B., Zhang, Z., Chen, W., 2015. Occurrence, bioaccumulation, and trophic magnification of pharmaceutically active compounds in Taihu Lake, China. Chemosphere 138, 140-147. https://doi.org/10.1016/j.chemosphere.2015.05.086.
|
Yang, Y., Ok, Y.S., Kim, K.H., Kwon, E.E., Tsang, Y.F., 2017. Occurrences and removal of pharmaceuticals and personal care products(PPCPs) in drinking water and water/sewage treatment plants: A review. Sci. Total Environ. 596, 303-320. https://doi.org/10.1016/j.scitotenv.2017.04.102.
|
Ying, G.G., He, L.Y., Ying, A.J., Zhang, Q.Q., Liu, Y.S., Zhao, J.L., 2017. China must reduce its antibiotic use. Environ. Sci. Technol. 51(3), 1072-1073. https://doi.org/10.1021/acs.est.6b06424.
|
Yoon, Y., Ryu, J., Oh, J., Choi, B.G., Snyder, S.A., 2010. Occurrence of endocrine disrupting compounds, pharmaceuticals, and personal care products in the Han River (Seoul, South Korea). Sci. Total Environ. 408(3), 636-643. https://doi.org/10.1016/j.scitotenv.2009.10.049.
|
Zabiegala, B., Kot-Wasik, A., Urbanowicz, M., Namiesnik, J., 2010. Passive sampling as a tool for obtaining reliable analytical information in environmental quality monitoring. Anal. Bioanal. Chem. 396(1), 273-296. https://doi.org/10.1007/s00216-009-3244-4.
|
Zha, D.P., Li, Y., Wang, L., Yang, C.M., Lu, G.H., 2017. Occurrence and attenuation of pharmaceuticals and their transformation products in rivers impacted by sewage treatment plants. RSC Adv. 7(65), 40905-40913. https://doi.org/10.1039/c7ra06852b.
|
Zhang, K., Zhao, Y.B., Fent, K., 2016. Occurrence and ecotoxicological effects of free, conjugated, and halogenated steroids including 17a-hydroxypregnanolone and pregnanediol in Swiss wastewater and surface water. Environ. Sci. Technol. 51(11), 6498-6506. https://doi.org/10.1021/acs.est.7b01231.
|
Zhang, Z.L., Hibberd, A., Zhou, J.L., 2008. Analysis of emerging contaminants in sewage effluent and river water: Comparison between spot and passive sampling. Anal. Chim. Acta 607(1), 37-44. https://doi.org/10.1016/j.aca.2007.11.024.
|
Zhao, Y.B., Zhang, K., Fent, K., 2016. Corticosteroid fludrocortisone acetate targets multiple end points in zebrafish (Danio rerio) at low concentrations. Environ. Sci. Technol. 50(18), 10245-10254. https://doi.org/10.1021/acs.est.6b03436.
|
Zhu, F., Yao, Z.J., Ji, W.L., Liu, D.Y., Zhang, H., Li, A.M., Huo, Z.L., Zhou, Q., 2020. An efficient resin for solid-phase extraction and determination by UPLC-MS/MS of 44 pharmaceutical personal care products in environmental waters. Front. Environ. Sci. Eng. 14(3), 1-11. https://doi.org/10.1007/s11783-020-1228-y.
|
Zhu, F., Wang, S.Q., Liu, Y.J., Wu, M.H., Wang, H.Y., Xu, G., 2021. Antibiotics in the surface water of Shanghai, China: Screening, distribution, and indicator selecting. Environ. Sci. Pollut. Res. 28, 9836-9848. https://doi.org/10.1007/s11356-020-10967-x.
|